How a Properly Functioning Immune System Plays an Important Role in the Reduction of the Aging Process.
The immune system is the primary defense against aging. Immune dysfunction, particularly senescence, contributes to oxidative stress through oxygen stress-related immune system dysfunction. This leads to an overproduction of;
- Reactive Oxygen Species (ROS): Reactive oxygen species (ROS) are highly reactive molecules containing oxygen that are produced naturally in our bodies as a byproduct of normal cellular processes, like breathing and converting food into energy. It is also known as a “Free Radical”. However, they are very important to eliminating the pathogens, that cause disease and death[i]–[ii]. They have important antimicrobial properties. The term antimicrobial includes viruses, bacteria and fungi. Think of ROS as tiny, unstable particles that are very important to warding off disease, however they can cause damage to cells, proteins, and DNA if their levels get too high. While our bodies have systems in place to neutralize and balance ROS, factors like pollution, e. forever chemicals, smoking, and stress can lead to an excess, contributing to aging and various diseases. Radiation, both ionizing (nuclear) [iii]–[iv]–[v] and non-ionizing (EMF, radio, cellphone, etc…)[vi]–[vii].is another major cause of ROS. Essentially, ROS are like the “exhaust fumes” of our body’s energy production that need to be managed to keep our cells healthy.
- Reactive Nitrogen Species (RNS): Reactive nitrogen species (RNS) are a group of nitrogen-based molecules that are highly reactive due to their chemical structure. In simpler terms, they are unstable forms of nitrogen that can easily interact with other molecules in the body. Like ROS, RNS can be both beneficial and harmful: they play important roles in cell signaling and defense against infections but can also cause damage to cells and tissues if their levels become too high, leading to conditions like inflammation, neurodegenerative disorders and oxidative stress. Examples of RNS include nitric oxide (NO) and peroxynitrite (ONOO-)[viii]–[ix][x].
When imbalance occurs, “Exacerbating Oxidative Stress” may result. This means increasing the damage caused by an imbalance between free radicals (unstable molecules that can damage cells) and antioxidants (molecules that can neutralize free radicals) in the body. When this balance tips towards too many free radicals and not enough antioxidants, it leads to oxidative stress. This can worsen and cause harm to cells, proteins, and DNA, potentially leading to various diseases like cancer, heart disease, and aging-related issues. Factors such as poor diet, pollution, smoking, and prolonged stress can make oxidative stress worse.
What is the Key to Keeping Your Immune System in Balance? The yin and the yang, the road of neutrality. (Create a ying and yang meme that talks about balance and the road to neutrality.
One compound appears to support the needs of keeping the immune system in balance. It has been shown to act as a regulator of the immune system. i.e. modulator, with a history going back to the 1940’s.
Historically, what did the masses survive on?
Baker’s Yeast
History and Benefits of Baker’s Yeast (Saccharomyces cerevisiae) Derived Beta 1-3D Glucan
History: Baker’s yeast, scientifically known as Saccharomyces cerevisiae, has been used for centuries in baking and brewing. However, its health benefits, particularly the immune-modulating properties[xi] of its cell wall component, beta 1-3D glucan, have only been studied since the 1950’s. This specific type of beta glucan has been found to have multiple health benefits, including reducing oxidative stress, glycation, telomere shortening, side reactions, mutations, and protein aggregation. It has also been shown to protect against radiation induced aging[xii]–[xiii]–[xiv]
Oxidative Stress: Beta 1-3D glucan from baker’s yeast can reduce oxidative stress by enhancing the activity of antioxidant enzymes and scavenging free radicals, thus protecting cells from oxidative damage[xv], reduce the levels of reactive oxygen species (ROS)[xvi] and chemically induced oxidative stress, i.e. forever chemicals and such[xvii].
Glycation: Glycation is a process where sugar molecules bind to proteins or lipids, leading to the formation of harmful advanced glycation end-products (AGEs). Beta 1-3D glucan has been shown to effectively inhibit the glycation process, thereby reducing the formation of AGEs, thereby protecting tissues and organs from damage[xviii]–[xix]–[xx].
Telomere Shortening: Telomeres protect chromosome ends from deterioration. Beta 1-3D glucan can support cellular health and longevity by reducing oxidative stress and inflammation, factors that contribute to telomere shortening[xxi]–[xxii]–[xxiii]. Oxidative stress directly damages the telomeric DNA, while chronic inflammation increases cellular turnover and stress, both of which accelerate telomere attrition[xxiv]–[xxv]–[xxvi]–[xxvii]. By reducing oxidative stress, chronic inflammation and enhancing immune function and cellular health telomere shortening appear to be minimized.
Side Reactions: Beta 1-3D glucan helps minimize adverse side reactions by modulating immune responses and reducing inflammation, which can often be a source of harmful side effects in various conditions and treatments. PFAS can induce oxidative stress[xxviii] and activate inflammation pathways[xxix]. Bisphenol A (BPA) exposure during embryonic/fetal life and infancy increases oxidative stress and causes brain damage[xxx] and endocrine disruption and metabolic disorders[xxxi]. Heavy metals such as lead, mercury, and cadmium induce oxidative stress and inflammation, leading to cellular and systemic toxicity[xxxii] and contribute to chronic diseases and acute toxicity[xxxiii]. Ionizing radiation generates oxidative stress, leading to prolonged cellular damage and increased risk of cancer[xxxiv]–[xxxv][xxxvi].
Mutations: By protecting DNA from oxidative damage and enhancing DNA repair mechanisms, beta 1-3D glucan can help reduce the occurrence of genetic mutations[xxxvii]. Reactive oxygen species (ROS) lead to mutations, which are shown to initiate and cause the progression of cancer[xxxviii]–[xxxix]. Beta 1-3d glucan has been shown to reduce the levels of reactive oxygen species (ROS)[xl]–[xli].
Protein Aggregation: Also called Prion Disease, Creutzfeldt-Jakob Disease (CJD), Gerstmann-Sträussler-Scheinker Syndrome (GSS), Fatal Familial Insomnia (FFI) and Kuru (caused by cannibalism)[xlii]. It can lead to diseases like Alzheimer’s and Parkinson’s. Beta 1-3D glucan can reduce protein aggregation by promoting proper protein folding and reducing oxidative stress[xliii].
Beta 1-3D glucan derived from baker’s yeast (Saccharomyces cerevisiae) has a rich history of use and a broad range of health benefits. It can help reduce oxidative stress, glycation, telomere shortening, side reactions, mutations, and protein aggregation. The benefits of a high-quality low-cost Beta 1 3d glucan supplement make it a valuable supplement for supporting overall. The market is full of substandard cost Beta 1 3d glucan supplement. Discover how to compare and identify for yourself a high quality beta glucan supplement by clicking here.
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