Nicotine, is it the Most Suppress Nutrient in the History of the Earth?

Nicotine, commonly associated with tobacco products, has long been demonized for its addictive properties and detrimental health effects. Are you aware that nicotine is not addictive? In 1994 the CEO’s of the big Tabacco companies testified under oath to the US Congress that Nicotine is not addictive.

Six months later the Department of Justice launched a perjury investigation. However, it concluded that there wasn’t sufficient evidence for perjury charges since the CEOs stated under oath that they “believed” nicotine wasn’t addictive, thus avoiding prosecution. Where have we heard that before? I guess it all depends on what the definition of is…is.

Did the CEO’s commit perjury, or did they know something that the rest of American did not?  Many believed they knew something, and that something was in fact that Nicotine was not addictive? In 1995 that theory that nicotine was not addictive was proven correct.

Soon after the congressional testimony Harvard decided to investigate the claim of the CEO’s that nicotine was not addictive. They commenced a study and discovered that the CEO’s did not commit perjury. Nicotine was not addictive. The study, titled “A study of pyrazines in cigarettes and how additives might be used to enhance tobacco addiction.” was released in 1995 and was buried[i]. It was at least one of the 600+ additives[ii] in Tabacco that was the cause of it. When cigarettes are burned, they produce over 7,000 chemicals. Among them, at least 69 are recognized carcinogens, while numerous others have toxic properties[iii].

Tobacco has been used throughout history for medicinal purposes. When Columbus reached the Americas in 1492, he encountered tobacco use among the indigenous populations[iv]. This introduced tobacco to Europe, where it gained popularity for its stimulating effects.

From 1537 to 1559, publications in Europe[v] and Mexico frequently discussed the medicinal benefits of tobacco among the indigenous peoples of the New World. These accounts detailed its therapeutic use in treating various bodily ailments, including catarrh, colds, and fevers, as well as its role in aiding digestion and staving off hunger. It was still in use here in America as a medicinal until the 1920’s[vi].

Why has nicotine been demonized in recent history?

It wasn’t until the early 2020’s that nicotine started being seriously looked at for its medicinal properties. Past as well as recent studies emerged surrounding the presence of nicotine in everyday vegetables and its potential therapeutic benefits, particularly in the area of inflammatory diseases. This paradigm-shifting perspective helped uncover an agenda to hide the incredible benefits it had to offer.

One of the most intriguing revelations is the ubiquitous presence of nicotine in various vegetables, including eggplants, tomatoes, celery, and cauliflower, as well as white potatoes. Despite this widespread occurrence, addiction to these foods is virtually non-existent, raising questions about the narrative surrounding nicotine’s role in health and disease. Click here to discover the foods that contain nicotine.  To discover foods that contain nicotine and the amounts click here. 

LINK TO FOODS CONTAING NICOTINE

The conventional medical advice to avoid nightshade vegetables for inflammatory conditions like arthritis has long been ingrained in medical practice. However, an alternative viewpoint suggests that nicotine, present in these vegetables, may actually offer therapeutic relief for such conditions. This challenges the prevailing narrative and calls for a closer examination of the potential benefits of nicotine in managing inflammatory diseases[vii].

Emerging research has shed light on nicotine’s anti-inflammatory properties, demonstrating its efficacy in alleviating symptoms associated with various conditions, including;

  • Alzheimer’s: “It is clear that nicotine has long-lasting effects on neuronal signaling that contribute to its neuroprotective effects.” [viii][ix]
  • Autism: “Here we report the use of transdermal nicotine as an adjunctive medication to treat aggression in a hospitalized adolescent with ASD. Nicotine patch was recurrently well tolerated, and reduced the need for emergency medication and restraint.” [x][xi][xii]
  • Brain Cancer: “These results suggest that NA treatment may be developed into a potential therapy for malignant glioma”[xiii]
  • Cognitive Function: “improvement in primary and secondary cognitive measures of attention, memory, and mental processing”[xiv]
  • Type I Diabetes: “reduces the incidence of type I diabetes”[xv]
  • Impaired Learning and Memory:showed significant nicotine-induced improved performance”[xvi]
  • Multiple Sclerosis: “decreased risk of developing MS”, “reduced clinical symptoms[xvii][xviii]
  • Parkinson’s Disease: [xix][xx]
  • Myocarditis: “The survival rate on day 14 increased in a dose-dependent fashion and was markedly higher[xxi]
  • Schizophrenia:nicotine may represent a therapeutic strategy for the treatment of schizophrenia” [xxii][xxiii]

In one study “Nicotine may be suggested as a potential preventive agent against Covid-19 infection. Both the epidemiological/clinical evidence and the in silico findings may suggest that Covid-19 infection is a nAChR disease that could be prevented and may be controlled by nicotine.”[xxiv]

Healthcare professionals often overlook nicotine as a treatment option, opting instead for conventional pharmaceutical interventions. This reluctance to explore alternative therapies deprives patients of potentially effective treatments and highlights the need for a paradigm shift in thinking.

Anecdotal accounts of individuals experiencing remarkable improvements in their health after using nicotine patches or gum serve as compelling testimony to its therapeutic potential. From the reversal of Parkinson’s symptoms to the resolution of long-hauler COVID symptoms, these stories underscore the need for further exploration of nicotine’s medicinal properties.

However, caution is warranted, as excessive nicotine exposure can lead to adverse effects. A participant’s experience of nausea and vomiting from overuse highlights the importance of proper dosage and supervision when using nicotine as a therapeutic agent.

Despite concerns about addiction, studies have shown that participants did not develop a dependence on nicotine after using patches. Long-term relief from symptoms without addiction further supports the argument for exploring nicotine as a viable treatment option for certain conditions.

Nicotine’s therapeutic potential poses challenges due to censorship and resistance from traditional medical establishments. The suppression of alternative viewpoints stifles progress and impedes access to potentially life-changing treatments.

In light of these revelations, there is a growing need to reexamine our understanding of nicotine and its role in health and disease. An upcoming presentation on nicotine’s therapeutic potential promises to provide further insights into its applications in various diseases, from autism to type 1 diabetes, offering hope for those in search of alternative treatments.

NEXT: Nightshade Vegetables: Loved, yet Hated by Healthcare, Why?

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Citations

[i] Alpert HR, Agaku IT, Connolly GN. A study of pyrazines in cigarettes and how additives might be used to enhance tobacco addiction. Tob Control. 2016 Jul;25(4):444-50. doi: 10.1136/tobaccocontrol-2014-051943. Epub 2015 Jun 10. PMID: 26063608; PMCID: PMC4941150.
[ii] https://www.healthline.com/health/smoking/whats-in-a-cigarette
[iii] Alpert HR, Agaku IT, Connolly GNA study of pyrazines in cigarettes and how additives might be used to enhance tobacco addictionTobacco Control 2016;25:444-450.
[iv] Charlton A. Medicinal uses of tobacco in history. J R Soc Med. 2004 Jun;97(6):292-6. doi: 10.1177/014107680409700614. PMID: 15173337; PMCID: PMC1079499.
[v] Thevet A. Les singularités de la France antarctique, autrement nomée Amerique & de plusieurs Terres & Isles decouvert de notre temps. Antwerp, 1558
[vi] SILVETTE H, LARSON PS, HAAG HB. Medical uses of tobacco, past and present. Va Med Mon (1918). 1958 Sep;85(9):472-84. PMID: 13581502.
[vii] Zhang W, Lin H, Zou M, Yuan Q, Huang Z, Pan X, Zhang W. Nicotine in Inflammatory Diseases: Anti-Inflammatory and Pro-Inflammatory Effects. Front Immunol. 2022 Feb 18;13:826889. doi: 10.3389/fimmu.2022.826889. PMID: 35251010; PMCID: PMC8895249.
[viii] Picciotto MR, Zoli M. Neuroprotection via nAChRs: the role of nAChRs in neurodegenerative disorders such as Alzheimer’s and Parkinson’s disease. Front Biosci. 2008;13:492-504.
[ix] https://news.vumc.org/2015/10/29/study-explores-nicotine-patch-to-treat-memory-loss/
[x] Van Schalkwyk GI, Lewis AS, Qayyum Z, Koslosky K, Picciotto MR, Volkmar FR. Reduction of Aggressive Episodes After Repeated Transdermal Nicotine Administration in a Hospitalized Adolescent with Autism Spectrum Disorder. J Autism Dev Disord. 2015 Sep;45(9):3061-6. doi: 10.1007/s10803-015-2471-0. PMID: 25982311; PMCID: PMC4755349.
[xi] Lewis AS, van Schalkwyk GI, Lopez MO, Volkmar FR, Picciotto MR, Sukhodolsky DG. An Exploratory Trial of Transdermal Nicotine for Aggression and Irritability in Adults with Autism Spectrum Disorder. J Autism Dev Disord. 2018 Aug;48(8):2748-2757. doi: 10.1007/s10803-018-3536-7. PMID: 29536216; PMCID: PMC6394231.
[xii] Mahmood HM, Aldhalaan HM, Alshammari TK, Alqasem MA, Alshammari MA, Albekairi NA, AlSharari SD. The Role of Nicotinic Receptors in the Attenuation of Autism-Related Behaviors in a Murine BTBR T + tf/J Autistic Model. Autism Res. 2020 Aug;13(8):1311-1334. doi: 10.1002/aur.2342. Epub 2020 Jul 21. PMID: 32691528.
[xiii] Li, J., Qu, J., Shi, Y. et al. Nicotinic acid inhibits glioma invasion by facilitating Snail1 degradation. Sci Rep 7, 43173 (2017). https://doi.org/10.1038/srep43173
[xiv] Newhouse P, Kellar K, Aisen P, White H, Wesnes K, Coderre E, Pfaff A, Wilkins H, Howard D, Levin ED. Nicotine treatment of mild cognitive impairment: a 6-month double-blind pilot clinical trial. Neurology. 2012 Jan 10;78(2):91-101. doi: 10.1212/WNL.0b013e31823efcbb. PMID: 22232050; PMCID: PMC3466669.
[xv] Mabley JG, Pacher P, Southan GJ, Salzman AL, Szabó C. Nicotine reduces the incidence of type I diabetes in mice. J Pharmacol Exp Ther. 2002 Mar;300(3):876-81. doi: 10.1124/jpet.300.3.876. PMID: 11861793.
[xvi] Alzoubi, K.H., Aleisa, A.M., Gerges, N.Z. and Alkadhi, K.A. (2006), Nicotine reverses adult-onset hypothyroidism-induced impairment of learning and memory: Behavioral and electrophysiological studies. J. Neurosci. Res., 84: 944-953. https://doi.org/10.1002/jnr.21014
[xvii] Hedström AK, Hillert J, Olsson T, Alfredsson L. Nicotine might have a protective effect in the etiology of multiple sclerosis. Mult Scler. 2013 Jul;19(8):1009-13. doi: 10.1177/1352458512471879. Epub 2013 Jan 14. PMID: 23319071.
[xviii] https://mscanada.ca/ms-research/latest-research/ms-society-funded-study-shows-that-nicotine-reduces-the-invasion-of
[xix] https://www.medscape.com/viewarticle/718409?form=fpf
[xx] https://www.sciencedaily.com/releases/2010/03/100310162823.htm
[xxi] Li-Sha G, Jing-Lin Z, Guang-Yi C, Li L, De-Pu Z, Yue-Chun L. Dose-dependent protective effect of nicotine in a murine model of viral myocarditis induced by coxsackievirus B3. Sci Rep. 2015 Oct 28;5:15895. doi: 10.1038/srep15895. Erratum in: Sci Rep. 2015;5:17247. PMID: 26507386; PMCID: PMC4623743.
[xxii] Koukouli F, Rooy M, Tziotis D, Sailor KA, O’Neill HC, Levenga J, Witte M, Nilges M, Changeux JP, Hoeffer CA, Stitzel JA, Gutkin BS, DiGregorio DA, Maskos U. Nicotine reverses hypofrontality in animal models of addiction and schizophrenia. Nat Med. 2017 Mar;23(3):347-354. doi: 10.1038/nm.4274. Epub 2017 Jan 23. PMID: 28112735; PMCID: PMC5819879.
[xxiii] Waterhouse U, Brennan KA, Ellenbroek BA. Nicotine self-administration reverses cognitive deficits in a rat model for schizophrenia. Addict Biol. 2018 Mar;23(2):620-630. doi: 10.1111/adb.12517. Epub 2017 May 12. PMID: 28497655.
[xxiv] Changeux JP, Amoura Z, Rey FA, Miyara M. A nicotinic hypothesis for Covid-19 with preventive and therapeutic implications. C R Biol. 2020 Jun 5;343(1):33-39. doi: 10.5802/crbiol.8. PMID: 32720486.